Hereditary breast cancer the implications of

Sign up now Genetic testing for breast cancer: Psychological and social impact Genetic testing to estimate breast and ovarian cancer risk may prompt many emotional and psychological reactions.

Hereditary breast cancer the implications of

Sign up now Genetic testing for breast cancer: Psychological and social impact Genetic testing to estimate breast and ovarian cancer risk may prompt many emotional and psychological reactions.

The psychological, emotional and social implications of genetic testing also are worth considering, both for yourself and for members of your family. Positive test results If genetic testing reveals a BRCA gene mutation, you might experience a range of responses to learning your test results, including: Anxiety about developing cancer.

Relief of knowing your risk status. You may view your test results in a positive light: You can step up cancer surveillance efforts or take risk-reducing steps, such as preventive surgery or medications.

You also have the potential to inform and educate family members who may be affected. Guilt about passing a gene mutation on to your child. Learning your genetic status may prompt fears that your child or children also have inherited the gene mutation.

If you learn that you are a carrier of the breast cancer gene, this can lead to more questions and anxiety about when is the best time to discuss the results with your children.

Hereditary breast cancer the implications of

Stress over major medical decisions. Discussing options with a genetic counselor, breast specialist or oncologist can help guide you.

Causes of Cancer – Genetic Mutations | BRCA & HBOC Mutations

Concerns over health insurance discrimination. In the United States, the federal Genetic Information Nondiscrimination Act of protects individuals who undergo genetic testing.

It prohibits insurers from denying health insurance or raising premium or contribution rates on the basis of genetic information.

The law also covers protection from employment discrimination. Talk about these — or any other — concerns with your genetic counselor, doctor or other health care provider. Negative test results Learning that genetic testing found no alteration in the BRCA genes might produce feelings of: It would be a mistake to let your negative test results lull you into a false sense of security.

You still face the same level of cancer risk as the general population — or maybe slightly higher because of your family history — and that makes your odds about 1 in 8 for developing breast cancer during your lifetime. Testing negative for a BRCA mutation may bring on feelings of guilt — especially if other family members do carry the mutation and face an increased cancer risk.

Uncertainty about your cancer risk. Receiving a negative test result might not allow your doctor to draw a definite conclusion about your risk status. This is known as a variant of uncertain significance.

Learning that you have a genetic variant of unknown significance may lead to: Confusion and anxiety about your cancer risk Frustration over the lack of accurate individualized cancer risk information Challenges with making cancer screening, treatment and prevention decisions Living with test results Most people would be anxious if given the chance to find out whether their risk of a serious disease was higher than average.

You have time to research and understand all your options before making a decision. For many, simply knowing their risk status eases psychological and emotional distress. They can be proactive and establish a personalized plan to deal with their increased risk.Race: Breast cancer is diagnosed more often in caucasian women than women of other races.

Family History and Genetic Factors: If your mother, sister, father or child has been diagnosed with breast or ovarian cancer, you have a higher risk of being diagnosed with breast cancer in the future. Your risk increases if your relative was diagnosed before the age of Management of patients at high risk for hereditary breast cancer (HBC) must critically assess its phenotypic and genotypic heterogeneity, particularly evidenced by the varying spectra of cancer sites that are integral to the respective HBC syndromes.

Hereditary breast cancer the implications of

No one should face hereditary cancer alone. Thinking about cancer or dealing with cancer risk can be scary or overwhelming, but we believe that receiving information and resources is comforting, empowering, and lifesaving. About 5% to 10% of breast cancers are thought to be hereditary, caused by abnormal genes passed from parent to child.

Most inherited cases of breast cancer are associated with mutations in two genes: BRCA1 and BRCA2. Learn more about genetic mutations linked to breast cancer. Hereditary Breast Cancer: The Implications of Genetic Mutations Nicole Kownacki Felician College Abstract The purpose of this paper is to examine the role genetics play related to hereditary breast cancer and the options available for risk reduction and prevention.

If the test is positive, there is still a 15% to 20% chance of not developing breast cancer. Genetic testing is costly, ranging from about $ to more than $3,, depending on the type of test.

Risk Factors - National Breast Cancer Foundation